Whole exome sequencing of multiple meningiomas with varying histopathological presentation in one patient revealed distinctive somatic mutation burden and independent clonal origins

Background: Although meningiomas are common intracranial tumors, multiple meningiomas (MMs) are rare entities in patients without neurofibromatosis type 2. Previous studies suggest most sporadic MMs are of monoclone in origin. Objective: To elucidate the clonal relationship between two sporadic menin...

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Detalles Bibliográficos
Autores principales: Sheng, Han-Song, Shen, Fang, Zhang, Nu, Yu, Li-Sheng, Lu, Xiang-Qi, Zhang, Zhe, Fang, Huang-Yi, Zhou, Ling-Li, Lin, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510395/
https://www.ncbi.nlm.nih.gov/pubmed/31123420
http://dx.doi.org/10.2147/CMAR.S202394

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