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STAT6 knockdown using multiple siRNA sequences inhibits proliferation and induces apoptosis of human colorectal and breast cancer cell lines
The transcription factor STAT6 is strongly expressed in various tumours and is most highly expressed in human malignant lymphomas and pancreatic, colorectal, prostate and breast cancers. STAT6 is associated with cancer cell proliferation, an increased malignancy and poor prognosis. Thus, techniques...
Autores principales: | Salguero-Aranda, Carmen, Sancho-Mensat, Daniel, Canals-Lorente, Beatriz, Sultan, Sabena, Reginald, Ajan, Chapman, Lee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510441/ https://www.ncbi.nlm.nih.gov/pubmed/31075146 http://dx.doi.org/10.1371/journal.pone.0207558 |
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