Cargando…

Crosstalks of the PTPIP51 interactome revealed in Her2 amplified breast cancer cells by the novel small molecule LDC3/Dynarrestin

LDC3/Dynarrestin, an aminothiazole derivative, is a recently developed small molecule, which binds protein tyrosine phosphatase interacting protein 51 (PTPIP51). PTPIP51 interacts with various proteins regulating different signaling pathways leading to proliferation and migration. Her2 positive brea...

Descripción completa

Detalles Bibliográficos
Autores principales: Dietel, Eric, Brobeil, Alexander, Delventhal, Lucas, Tag, Claudia, Gattenlöhner, Stefan, Wimmer, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510450/
https://www.ncbi.nlm.nih.gov/pubmed/31075141
http://dx.doi.org/10.1371/journal.pone.0216642