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I_MDS: an inflammatory bowel disease molecular activity score to classify patients with differing disease-driving pathways and therapeutic response to anti-TNF treatment

Crohn’s disease and ulcerative colitis are driven by both common and distinct underlying mechanisms of pathobiology. Both diseases, exhibit heterogeneity underscored by the variable clinical responses to therapeutic interventions. We aimed to identify disease-driving pathways and classify individual...

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Detalles Bibliográficos
Autores principales: Pavlidis, Stelios, Monast, Calixte, Loza, Matthew J., Branigan, Patrick, Chung, Kiang F., Adcock, Ian M., Guo, Yike, Rowe, Anthony, Baribaud, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510457/
https://www.ncbi.nlm.nih.gov/pubmed/31039157
http://dx.doi.org/10.1371/journal.pcbi.1006951