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I_MDS: an inflammatory bowel disease molecular activity score to classify patients with differing disease-driving pathways and therapeutic response to anti-TNF treatment
Crohn’s disease and ulcerative colitis are driven by both common and distinct underlying mechanisms of pathobiology. Both diseases, exhibit heterogeneity underscored by the variable clinical responses to therapeutic interventions. We aimed to identify disease-driving pathways and classify individual...
Autores principales: | Pavlidis, Stelios, Monast, Calixte, Loza, Matthew J., Branigan, Patrick, Chung, Kiang F., Adcock, Ian M., Guo, Yike, Rowe, Anthony, Baribaud, Frédéric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510457/ https://www.ncbi.nlm.nih.gov/pubmed/31039157 http://dx.doi.org/10.1371/journal.pcbi.1006951 |
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