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Sjogren's Syndrome: Clinical Benefits of Low-dose Naltrexone Therapy

Sjogren’s Syndrome is a chronic autoimmune disorder that causes the inflammation of the lacrimal and salivary glands, resulting in dryness of the eyes and mouth. In addition, fatigue and musculoskeletal pain, often described as aching, is very common. Treatment directed toward alleviating the fatigu...

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Detalles Bibliográficos
Autor principal: Zashin, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510571/
https://www.ncbi.nlm.nih.gov/pubmed/31123647
http://dx.doi.org/10.7759/cureus.4225
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author Zashin, Scott
author_facet Zashin, Scott
author_sort Zashin, Scott
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description Sjogren’s Syndrome is a chronic autoimmune disorder that causes the inflammation of the lacrimal and salivary glands, resulting in dryness of the eyes and mouth. In addition, fatigue and musculoskeletal pain, often described as aching, is very common. Treatment directed toward alleviating the fatigue and pain associated with Sjogren’s is currently very limited. This report describes a case of a 47-year-old female with suspected Sjogren's based on long-standing dry eyes, dry mouth, joint pain, fatigue, elevated measures of inflammation, and a positive rheumatoid factor. She failed standard therapy but improved clinically with low-dose naltrexone therapy.
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spelling pubmed-65105712019-05-23 Sjogren's Syndrome: Clinical Benefits of Low-dose Naltrexone Therapy Zashin, Scott Cureus Internal Medicine Sjogren’s Syndrome is a chronic autoimmune disorder that causes the inflammation of the lacrimal and salivary glands, resulting in dryness of the eyes and mouth. In addition, fatigue and musculoskeletal pain, often described as aching, is very common. Treatment directed toward alleviating the fatigue and pain associated with Sjogren’s is currently very limited. This report describes a case of a 47-year-old female with suspected Sjogren's based on long-standing dry eyes, dry mouth, joint pain, fatigue, elevated measures of inflammation, and a positive rheumatoid factor. She failed standard therapy but improved clinically with low-dose naltrexone therapy. Cureus 2019-03-11 /pmc/articles/PMC6510571/ /pubmed/31123647 http://dx.doi.org/10.7759/cureus.4225 Text en Copyright © 2019, Zashin et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Zashin, Scott
Sjogren's Syndrome: Clinical Benefits of Low-dose Naltrexone Therapy
title Sjogren's Syndrome: Clinical Benefits of Low-dose Naltrexone Therapy
title_full Sjogren's Syndrome: Clinical Benefits of Low-dose Naltrexone Therapy
title_fullStr Sjogren's Syndrome: Clinical Benefits of Low-dose Naltrexone Therapy
title_full_unstemmed Sjogren's Syndrome: Clinical Benefits of Low-dose Naltrexone Therapy
title_short Sjogren's Syndrome: Clinical Benefits of Low-dose Naltrexone Therapy
title_sort sjogren's syndrome: clinical benefits of low-dose naltrexone therapy
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510571/
https://www.ncbi.nlm.nih.gov/pubmed/31123647
http://dx.doi.org/10.7759/cureus.4225
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