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Improvement of in vitro and early in utero porcine clone development after somatic donor cells are cultured under hypoxia

Genetically engineered pigs serve as excellent biomedical and agricultural models. To date, the most reliable way to generate genetically engineered pigs is via somatic cell nuclear transfer (SCNT), however, the efficiency of cloning in pigs is low (1–3%). Somatic cells such as fibroblasts frequentl...

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Detalles Bibliográficos
Autores principales:	Mordhorst, Bethany R., Benne, Joshua A., Cecil, Raissa F., Whitworth, Kristin M., Samuel, Melissa S., Spate, Lee D., Murphy, Clifton N., Wells, Kevin D., Green, Jonathan A., Prather, Randall S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510642/ https://www.ncbi.nlm.nih.gov/pubmed/30779254 http://dx.doi.org/10.1002/mrd.23132

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