Inhibition of tumour necrosis factor alpha in the R6/2 mouse model of Huntington’s disease by etanercept treatment

Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by the expansion of the CAG repeat in exon 1 of the huntingtin (HTT) gene, which results in a mutant protein with an extended polyglutamine tract. Inflammation occurs in both the brain and the periphery of HD patients and mo...

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Detalles Bibliográficos
Autores principales: Pido-Lopez, Jeffrey, Tanudjojo, Benedict, Farag, Sahar, Bondulich, Marie-Katrin, Andre, Ralph, Tabrizi, Sarah J., Bates, Gillian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510744/
https://www.ncbi.nlm.nih.gov/pubmed/31076648
http://dx.doi.org/10.1038/s41598-019-43627-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510744/
https://www.ncbi.nlm.nih.gov/pubmed/31076648
http://dx.doi.org/10.1038/s41598-019-43627-3

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