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Cancer-associated fibroblasts promote cisplatin resistance in bladder cancer cells by increasing IGF-1/ERβ/Bcl-2 signalling

While cancer-associated fibroblasts (CAFs) in the tumour microenvironment may play important roles in bladder cancer (BCa) progression, their impacts on BCa chemoresistance remain unclear. Using human BCa samples, we found that tumour tissues possessed more CAFs than did adjacent normal tissues. Bot...

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Detalles Bibliográficos
Autores principales:	Long, Xingbo, Xiong, Wei, Zeng, Xiting, Qi, Lin, Cai, Yi, Mo, Miao, Jiang, Huichuan, Zhu, Bisong, Chen, Zhi, Li, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510780/ https://www.ncbi.nlm.nih.gov/pubmed/31076571 http://dx.doi.org/10.1038/s41419-019-1581-6

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