Imaging of pulmonary perfusion using subtraction CT angiography is feasible in clinical practice

ABSTRACT: Subtraction computed tomography (SCT) is a technique that uses software-based motion correction between an unenhanced and an enhanced CT scan for obtaining the iodine distribution in the pulmonary parenchyma. This technique has been implemented in clinical practice for the evaluation of lu...

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Autores principales: Grob, Dagmar, Oostveen, Luuk J., Prokop, Mathias, Schaefer-Prokop, Cornelia M., Sechopoulos, Ioannis, Brink, Monique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Computed Tomography
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510874/
https://www.ncbi.nlm.nih.gov/pubmed/30255247
http://dx.doi.org/10.1007/s00330-018-5740-4
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author Grob, Dagmar
Oostveen, Luuk J.
Prokop, Mathias
Schaefer-Prokop, Cornelia M.
Sechopoulos, Ioannis
Brink, Monique
author_facet Grob, Dagmar
Oostveen, Luuk J.
Prokop, Mathias
Schaefer-Prokop, Cornelia M.
Sechopoulos, Ioannis
Brink, Monique
author_sort Grob, Dagmar
collection PubMed
description ABSTRACT: Subtraction computed tomography (SCT) is a technique that uses software-based motion correction between an unenhanced and an enhanced CT scan for obtaining the iodine distribution in the pulmonary parenchyma. This technique has been implemented in clinical practice for the evaluation of lung perfusion in CT pulmonary angiography (CTPA) in patients with suspicion of acute and chronic pulmonary embolism, with acceptable radiation dose. This paper discusses the technical principles, clinical interpretation, benefits and limitations of arterial subtraction CTPA. KEY POINTS: • SCT uses motion correction and image subtraction between an unenhanced and an enhanced CT scan to obtain iodine distribution in the pulmonary parenchyma. • SCT could have an added value in detection of pulmonary embolism. • SCT requires only software implementation, making it potentially more widely available for patient care than dual-energy CT.
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spelling pubmed-65108742019-05-28 Imaging of pulmonary perfusion using subtraction CT angiography is feasible in clinical practice Grob, Dagmar Oostveen, Luuk J. Prokop, Mathias Schaefer-Prokop, Cornelia M. Sechopoulos, Ioannis Brink, Monique Eur Radiol Computed Tomography ABSTRACT: Subtraction computed tomography (SCT) is a technique that uses software-based motion correction between an unenhanced and an enhanced CT scan for obtaining the iodine distribution in the pulmonary parenchyma. This technique has been implemented in clinical practice for the evaluation of lung perfusion in CT pulmonary angiography (CTPA) in patients with suspicion of acute and chronic pulmonary embolism, with acceptable radiation dose. This paper discusses the technical principles, clinical interpretation, benefits and limitations of arterial subtraction CTPA. KEY POINTS: • SCT uses motion correction and image subtraction between an unenhanced and an enhanced CT scan to obtain iodine distribution in the pulmonary parenchyma. • SCT could have an added value in detection of pulmonary embolism. • SCT requires only software implementation, making it potentially more widely available for patient care than dual-energy CT. Springer Berlin Heidelberg 2018-09-25 2019 /pmc/articles/PMC6510874/ /pubmed/30255247 http://dx.doi.org/10.1007/s00330-018-5740-4 Text en © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Computed Tomography
Grob, Dagmar
Oostveen, Luuk J.
Prokop, Mathias
Schaefer-Prokop, Cornelia M.
Sechopoulos, Ioannis
Brink, Monique
Imaging of pulmonary perfusion using subtraction CT angiography is feasible in clinical practice
title Imaging of pulmonary perfusion using subtraction CT angiography is feasible in clinical practice
title_full Imaging of pulmonary perfusion using subtraction CT angiography is feasible in clinical practice
title_fullStr Imaging of pulmonary perfusion using subtraction CT angiography is feasible in clinical practice
title_full_unstemmed Imaging of pulmonary perfusion using subtraction CT angiography is feasible in clinical practice
title_short Imaging of pulmonary perfusion using subtraction CT angiography is feasible in clinical practice
title_sort imaging of pulmonary perfusion using subtraction ct angiography is feasible in clinical practice
topic Computed Tomography
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510874/
https://www.ncbi.nlm.nih.gov/pubmed/30255247
http://dx.doi.org/10.1007/s00330-018-5740-4
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