Cargando…
Pazopanib may reduce bleeding in hereditary hemorrhagic telangiectasia
Pazopanib (Votrient) is an orally administered tyrosine kinase inhibitor that blocks VEGF receptors potentially serving as anti-angiogenic treatment for hereditary hemorrhagic telangiectasia (HHT). We report a prospective, multi-center, open-label, dose-escalating study [50 mg, 100 mg, 200 mg, and 4...
Autores principales: | Faughnan, Marie E., Gossage, James R., Chakinala, Murali M., Oh, S. Paul, Kasthuri, Raj, Hughes, Christopher C. W., McWilliams, Justin P., Parambil, Joseph G., Vozoris, Nicholas, Donaldson, Jill, Paul, Gitanjali, Berry, Pamela, Sprecher, Dennis L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510884/ https://www.ncbi.nlm.nih.gov/pubmed/30191360 http://dx.doi.org/10.1007/s10456-018-9646-1 |
Ejemplares similares
-
Pazopanib for severe bleeding and transfusion-dependent anemia in hereditary hemorrhagic telangiectasia
por: Parambil, Joseph G., et al.
Publicado: (2021) -
An international, multicenter study of intravenous bevacizumab for bleeding in hereditary hemorrhagic telangiectasia: the InHIBIT-Bleed study
por: Al-Samkari, Hanny, et al.
Publicado: (2020) -
Weekly epistaxis duration as an indicator of epistaxis severity in hereditary hemorrhagic telangiectasia—Preliminary results from a randomized controlled trial
por: Wu, Vincent, et al.
Publicado: (2021) -
Randomized, double-blind, placebo-controlled, crossover trial of oral doxycycline for epistaxis in hereditary hemorrhagic telangiectasia
por: Thompson, K. P., et al.
Publicado: (2022) -
Severity score for hereditary hemorrhagic telangiectasia
por: Latino, Giuseppe A, et al.
Publicado: (2014)