Cargando…
Characterisation of the Ral GTPase inhibitor RBC8 in human and mouse platelets
The Ral GTPases, RalA and RalB, have been implicated in numerous cellular processes, but are most widely known for having regulatory roles in exocytosis. Recently, we demonstrated that deletion of both Ral genes in a platelet-specific mouse gene knockout caused a substantial defect in surface exposu...
Autores principales: | Walsh, Tony G., Wersäll, Andreas, Poole, Alastair W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ltd
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510928/ https://www.ncbi.nlm.nih.gov/pubmed/30880223 http://dx.doi.org/10.1016/j.cellsig.2019.03.015 |
Ejemplares similares
-
Small GTPases in platelet membrane trafficking
por: Walsh, Tony G., et al.
Publicado: (2018) -
Antitumor Effects of Ral-GTPases Downregulation in Glioblastoma
por: Cemeli, Tània, et al.
Publicado: (2022) -
TD-60 links RalA GTPase function to the CPC in mitosis
por: Papini, Diana, et al.
Publicado: (2015) -
Ral GTPase is essential for actin dynamics and Golgi apparatus distribution in mouse oocyte maturation
por: Sun, Ming-Hong, et al.
Publicado: (2021) -
Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases
por: Hurd, Catherine A., et al.
Publicado: (2020)