First detection of the mcr-1 colistin resistance gene in Escherichia coli from a patient with urinary tract infection in Myanmar

Colistin-resistance gene mcr-1 was detected in an Escherichia coli sample among 442 clinical isolates collected in a tertiary-care hospital in Yangon, Myanmar, in 2018. This isolate was classified into phylogroup A–ST23 complex and harboured bla(CTX-M-15) and bla(TEM-1), associated with multiple mut...

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Detalles Bibliográficos
Autores principales: San, N., Aung, M.S., Thu, P.P., Myint, Y.Y., Aung, M.T., San, T., Mar, T.T., Lwin, M.M., Maw, W.W., Hlaing, M.S., Kobayashi, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510964/
https://www.ncbi.nlm.nih.gov/pubmed/31110773
http://dx.doi.org/10.1016/j.nmni.2019.100550
Descripción
Sumario:Colistin-resistance gene mcr-1 was detected in an Escherichia coli sample among 442 clinical isolates collected in a tertiary-care hospital in Yangon, Myanmar, in 2018. This isolate was classified into phylogroup A–ST23 complex and harboured bla(CTX-M-15) and bla(TEM-1), associated with multiple mutations in quinolone-resistance–determining regions in gyrA and parC.

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