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Tau covariance patterns in Alzheimer's disease patients match intrinsic connectivity networks in the healthy brain
According to the network model of neurodegeneration, the spread of pathogenic proteins occurs selectively along connected brain regions. We tested in vivo whether the distribution of filamentous tau (measured with [(18)F]flortaucipir-PET), fibrillar amyloid-β ([(11)C]PIB-PET) and glucose hypometabol...
Autores principales: | Ossenkoppele, Rik, Iaccarino, Leonardo, Schonhaut, Daniel R., Brown, Jesse A., La Joie, Renaud, O'Neil, James P., Janabi, Mustafa, Baker, Suzanne L., Kramer, Joel H., Gorno-Tempini, Maria-Luisa, Miller, Bruce L., Rosen, Howard J., Seeley, William W., Jagust, William J., Rabinovici, Gil D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510968/ https://www.ncbi.nlm.nih.gov/pubmed/31077982 http://dx.doi.org/10.1016/j.nicl.2019.101848 |
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