Cargando…

Elevated leptin levels induce inflammation through IL-6 in skeletal muscle of aged female rats

BACKGROUND: Chronic inflammation with aging contributes to sarcopenia. Previous studies have suggested that the accumulation of adipose tissue in skeletal muscle, referred to as intermuscular adipose tissue (IMAT), increases with age and is associated with inflammation. However, the mechanism govern...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tazawa, Ryo, Uchida, Kentaro, Fujimaki, Hisako, Miyagi, Masayuki, Inoue, Gen, Sekiguchi, Hiroyuki, Murata, Kosuke, Takata, Ken, Kawakubo, Ayumu, Takaso, Masashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511122/ https://www.ncbi.nlm.nih.gov/pubmed/31077169 http://dx.doi.org/10.1186/s12891-019-2581-5

Ejemplares similares

Relationships Between Spinal Alignment and Muscle Mass in Osteoporosis Patients Over 75 Years of Age Who Were Independent and Maintained Their Activities of Daily Living
por: Kawakubo, Ayumu, et al.
Publicado: (2021)

Increase in mast cell marker expression in the synovium of obese patients with osteoarthritis of the knee
por: Uchida, Kentaro, et al.
Publicado: (2019)

Reduced TGF-β Expression and CD206-Positive Resident Macrophages in the Intervertebral Discs of Aged Mice
por: Yokozeki, Yuji, et al.
Publicado: (2021)

Short-Term Impact of Staying Home on Bone Health in Patients With Osteoporosis During a State of Emergency Declaration Due to COVID-19 in Kanagawa, Japan
por: Yokozeki, Yuji, et al.
Publicado: (2020)

Hyaluronic Acid (800 kDa) Supplementation of University of Wisconsin Solution Improves Viability of Osteochondral Grafts and Reduces Matrix Metalloproteinase Expression during Cold Preservation
por: Yamada, Takuya, et al.
Publicado: (2015)

Basic Fibroblast Growth Factor-Anchored Multilayered Mesenchymal Cell Sheets Accelerate Periosteal Bone Formation
por: Uchida, Kentaro, et al.
Publicado: (2017)

TGF-β regulates nerve growth factor expression in a mouse intervertebral disc injury model
por: Yokozeki, Yuji, et al.
Publicado: (2021)

Nerve Growth Factor Regulation by TNF-α and IL-1β in Synovial Macrophages and Fibroblasts in Osteoarthritic Mice
por: Takano, Shotaro, et al.
Publicado: (2016)

The cytokine expression in synovial membrane and the relationship with pain and pathological findings at hip arthroscopy
por: Fukushima, Kensuke, et al.
Publicado: (2017)

Origin of M2 Mϕ and its macrophage polarization by TGF-β in a mice intervertebral injury model
por: Kawakubo, Ayumu, et al.
Publicado: (2022)

Acceleration of callus formation during fracture healing using basic fibroblast growth factor-kidney disease domain-collagen-binding domain fusion protein combined with allogenic demineralized bone powder
por: Saito, Wataru, et al.
Publicado: (2015)

Prevalence and Characteristics of Spinal Sagittal Malalignment in Patients with Osteoporosis
por: Matsunaga, Takayuki, et al.
Publicado: (2021)

Acceleration of bone union by in situ-formed hydrogel containing bone morphogenetic protein-2 in a mouse refractory fracture model
por: Shoji, Shintaro, et al.
Publicado: (2020)

Elevated macrophage-inducible C-type lectin expression in the synovial tissue of patients with rheumatoid arthritis
por: Takata, Ken, et al.
Publicado: (2021)

Elevation of MMP1 and ADAMTS5 mRNA expression in glenohumeral synovia of patients with hypercholesterolemia
por: Muneshige, Kyoko, et al.
Publicado: (2022)

Activation of calcitonin gene-related peptide signaling through the prostaglandin E2-EP1/EP2/EP4 receptor pathway in synovium of knee osteoarthritis patients
por: Minatani, Atsushi, et al.
Publicado: (2016)

Transforming growth factor-β stimulates nerve growth factor production in osteoarthritic synovium
por: Takano, Shotaro, et al.
Publicado: (2019)

TNF-α Suppresses Apelin Receptor Expression in Mouse Quadriceps Femoris-Derived Cells
por: Koyama, Tomohisa, et al.
Publicado: (2022)

Increase in Tryptase and Its Role in the Synovial Membrane of Overweight and Obese Patients with Osteoarthritis of the Knee
por: Takata, Ken, et al.
Publicado: (2020)

Possible Regulation of bFGF Expression by Mast Cells in Osteoarthritis Patients with Obesity: A Cross-Sectional Study
por: Takata, Ken, et al.
Publicado: (2021)

Transforming growth factor activating kinase 1 regulates extracellular matrix degrading enzymes and pain-related molecule expression following tumor necrosis factor-α stimulation of synovial cells: an in vitro study
por: Uchida, Kentaro, et al.
Publicado: (2017)

Total en bloc spondylectomy of the eleventh thoracic vertebra following denosumab therapy for the treatment of a giant cell tumor
por: Inoue, Gen, et al.
Publicado: (2017)

Body Composition in Japanese Girls with Adolescent Idiopathic Scoliosis
por: Miyagi, Masayuki, et al.
Publicado: (2020)

Acceleration of Bone Healing by In Situ-Forming Dextran-Tyramine Conjugates Containing Basic Fibroblast Growth Factor in Mice
por: Shoji, Shintaro, et al.
Publicado: (2020)

Effect of Bone Morphogenetic Protein-2 (BMP-2)/Hydroxyapatite/In Situ-Formed Hyaluronan Hydrogel Composites on Bone Formation in a Murine Model of Posterolateral Lumbar Fusion
por: Kuroda, Akiyoshi, et al.
Publicado: (2022)

Adrenomedullin Regulates IL-1β Gene Expression in F4/80+ Macrophages during Synovial Inflammation
por: Takano, Shotaro, et al.
Publicado: (2017)

Poly(POG)n loaded with recombinant human bone morphogenetic protein-2 accelerates new bone formation in a critical-sized bone defect mouse model
por: Tazawa, Ryo, et al.
Publicado: (2020)

Intraoperative Blood Loss at Different Surgical-Procedure Stages during Posterior Spinal Fusion for Idiopathic Scoliosis
por: Shirasawa, Eiki, et al.
Publicado: (2023)

Expression and regulation of macrophage-inducible C-type lectin in human synovial macrophages
por: Moriya, Mitsutoshi, et al.
Publicado: (2021)

Incidence of Unintentional Intraoperative Hypothermia in Pediatric Scoliosis Surgery and Associated Preoperative Risk Factors
por: Okamura, Maho, et al.
Publicado: (2020)

Perioperative Evaluation of Respiratory Muscle Strength after Scoliosis Correction in Patients with Duchenne Muscular Dystrophy
por: Saito, Wataru, et al.
Publicado: (2017)

Assessment of the duration and effectiveness of intra-articular lidocaine injections for groin pain in patients with labral tears involving early osteoarthritis
por: Fukushima, Kensuke, et al.
Publicado: (2021)

A High Body Mass Index and the Vacuum Phenomenon Upregulate Pain-Related Molecules in Human Degenerated Intervertebral Discs
por: Miyagi, Masayuki, et al.
Publicado: (2022)

Differential Synovial CGRP/RAMP1 Expression in Men and Women With Knee Osteoarthritis
por: Uchida, Kentaro, et al.
Publicado: (2021)

Effect of Single Injection of Recombinant Human Bone Morphogenetic Protein-2-Loaded Artificial Collagen-Like Peptide in a Mouse Segmental Bone Transport Model
por: Tazawa, Ryo, et al.
Publicado: (2019)

Increasing transforming growth factor-beta concentrations with age decrease apelin in the rat rotator cuff
por: Tazawa, Ryo, et al.
Publicado: (2021)

Regulation of calcitonin gene-related peptide expression through the COX-2/mPGES-1/PGE2 pathway in the infrapatellar fat pad in knee osteoarthritis
por: Aikawa, Jun, et al.
Publicado: (2018)

Expression of calcitonin gene-related peptide in the infrapatellar fat pad in knee osteoarthritis patients
por: Aikawa, Jun, et al.
Publicado: (2017)

Loop-Mediated Isothermal Amplification Screening for COVID-19 in Asymptomatic Preoperative Orthopedic Patients in a General Hospital in Kanagawa, Japan
por: Uchida, Kentaro, et al.
Publicado: (2020)

Osteoarthritis patients with high haemoglobin A1c have increased Toll-like receptor 4 and matrix metalloprotease-13 expression in the synovium
por: Murata, Kosuke, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_c2su7l2vv2a60mq4dkmpr22idj