Tissue-specific impact of stem-loops and quadruplexes on cancer breakpoints formation

BACKGROUND: Chromosomal rearrangements are the typical phenomena in cancer genomes causing gene disruptions and fusions, corruption of regulatory elements, damage to chromosome integrity. Among the factors contributing to genomic instability are non-B DNA structures with stem-loops and quadruplexes...

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Detalles Bibliográficos
Autores principales: Cheloshkina, Kseniia, Poptsova, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511154/
https://www.ncbi.nlm.nih.gov/pubmed/31077166
http://dx.doi.org/10.1186/s12885-019-5653-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511154/
https://www.ncbi.nlm.nih.gov/pubmed/31077166
http://dx.doi.org/10.1186/s12885-019-5653-x

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