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Hypoxia-inducible factor-1α induces CX3CR1 expression and promotes the epithelial to mesenchymal transition (EMT) in ovarian cancer cells

BACKGROUND: Chemokines are involved in the homing of various cancer cells, including those of ovarian cancer (OvCa), to distant organs. They may also promote or inhibit cancer progression and metastasis. Hypoxia, a common phenomenon in malignant tumors, promotes cell proliferation regulated by HIF-1...

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Detalles Bibliográficos
Autores principales: Singh, Santosh Kumar, Mishra, Manoj Kumar, Singh, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511167/
https://www.ncbi.nlm.nih.gov/pubmed/31077234
http://dx.doi.org/10.1186/s13048-019-0517-1