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Metformin regulates lipid metabolism in a canine model of atrial fibrillation through AMPK/PPAR-α/VLCAD pathway

BACKGROUND: Atrial lipid metabolic remodeling is critical for the process of atrial fibrillation (AF). Abnormal Fatty acid (FA) metabolism in cardiomyocytes is involved in the pathogenesis of AF. MET (Metformin), an AMPK (AMP-activated protein kinase) activator, has been found to be associated with...

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Detalles Bibliográficos
Autores principales:	Bai, Fan, Liu, Yaozhong, Tu, Tao, Li, Biao, Xiao, Yichao, Ma, Yingxu, Qin, Fen, Xie, Jing, Zhou, Shenghua, Liu, Qiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511207/ https://www.ncbi.nlm.nih.gov/pubmed/31077199 http://dx.doi.org/10.1186/s12944-019-1059-7

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