Dimethyl fumarate ameliorates cisplatin-induced renal tubulointerstitial lesions

Dimethyl fumarate (DMF) has an antioxidant effect by activating the nuclear factor erythroid 2-related transcription factor 2 (Nrf2). Cisplatin (CIS) has nephrotoxicity as a frequently associated side effect that is mainly mediated by oxidative stress. In this study, we investigated whether the DMF-...

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Detalles Bibliográficos
Autores principales: Sasaki, Ayaka, Koike, Natsumi, Murakami, Tomoaki, Suzuki, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511538/
https://www.ncbi.nlm.nih.gov/pubmed/31092974
http://dx.doi.org/10.1293/tox.2018-0049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511538/
https://www.ncbi.nlm.nih.gov/pubmed/31092974
http://dx.doi.org/10.1293/tox.2018-0049

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