Binding of the regulatory domain of MutL to the sliding β-clamp is species specific

The β-clamp is a protein hub central to DNA replication and fork management. Proteins interacting with the β-clamp harbor a conserved clamp-binding motif that is often found in extended regions. Therefore, clamp interactions have –almost exclusively– been studied using short peptides recapitulating...

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Detalles Bibliográficos
Autores principales: Almawi, Ahmad W, Scotland, Michelle K, Randall, Justin R, Liu, Linda, Martin, Heather K, Sacre, Lauralicia, Shen, Yao, Pillon, Monica C, Simmons, Lyle A, Sutton, Mark D, Guarné, Alba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511837/
https://www.ncbi.nlm.nih.gov/pubmed/30916336
http://dx.doi.org/10.1093/nar/gkz115

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