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Growth suppression by altered (p)ppGpp levels results from non-optimal resource allocation in Escherichia coli
Understanding how bacteria coordinate gene expression with biomass growth to adapt to various stress conditions remains a grand challenge in biology. Stress response is often associated with dramatic accumulation of cellular guanosine tetra- or penta-phosphate (p)ppGpp (also known as ‘magic spot’),...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511861/ https://www.ncbi.nlm.nih.gov/pubmed/30916318 http://dx.doi.org/10.1093/nar/gkz211 |