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Esc2 promotes telomere stability in response to DNA replication stress

Telomeric regions of the genome are inherently difficult-to-replicate due to their propensity to generate DNA secondary structures and form nucleoprotein complexes that can impede DNA replication fork progression. Precisely how cells respond to DNA replication stalling within a telomere remains poor...

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Detalles Bibliográficos
Autores principales:	Jørgensen, Signe W, Liberti, Sascha E, Larsen, Nicolai B, Lisby, Michael, Mankouri, Hocine W, Hickson, Ian D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511870/ https://www.ncbi.nlm.nih.gov/pubmed/30838410 http://dx.doi.org/10.1093/nar/gkz158

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