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Novel 15-Lipoxygenase-1 Inhibitor Protects Macrophages from Lipopolysaccharide-Induced Cytotoxicity

[Image: see text] Various mechanisms for regulated cell death include the formation of oxidative mediators such as lipid peroxides and nitric oxide (NO). In this respect, 15-lipoxygenase-1 (15-LOX-1) is a key enzyme that catalyzes the formation of lipid peroxides. The actions of these peroxides are...

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Detalles Bibliográficos
Autores principales:	Guo, Hao, Verhoek, Iris C., Prins, Gerian G. H., van der Vlag, Ramon, van der Wouden, Petra E., van Merkerk, Ronald, Quax, Wim J., Olinga, Peter, Hirsch, Anna K. H., Dekker, Frank J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511944/ https://www.ncbi.nlm.nih.gov/pubmed/30964295 http://dx.doi.org/10.1021/acs.jmedchem.9b00212

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