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Microglial BDNF, PI3K, and p-ERK in the Spinal Cord Are Suppressed by Pulsed Radiofrequency on Dorsal Root Ganglion to Ease SNI-Induced Neuropathic Pain in Rats

BACKGROUND: Pulsed radiofrequency (PRF) on the dorsal root ganglion (DRG) has been applied to alleviate neuropathic pain effectively, yet the mechanisms underlying pain reduction owing to this treatment are not clarified completely. The activated microglia, brain-derived neurotrophic factor (BDNF),...

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Detalles Bibliográficos
Autores principales: Xu, Xueru, Fu, Shaoxiong, Shi, Xiaomei, Liu, Rongguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512068/
https://www.ncbi.nlm.nih.gov/pubmed/31182984
http://dx.doi.org/10.1155/2019/5948686