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The Dosage of the Derivative of Clostridium Ghonii (DCG) Spores Dictates Whether an IFNγ/IL-9 or a Strong IFNγ Response Is Elicited in TC-1 Tumour Bearing Mice
BACKGROUND: Anaerobic Clostridial spores (CG) cause significant oncolysis in hypoxic tumour microenvironment and result in tumour regression in both animal models and clinical trials. The immune mediated response plays a critical role in the antitumour effect by the anaerobic spore treatment. METHOD...
Autores principales: | Ni, Guoying, Wang, Yong, Good, David, Yuan, Jianwei, Pan, Xuan, Wei, Jou, Liu, Xiaosong, Wei, Ming Q. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512072/ https://www.ncbi.nlm.nih.gov/pubmed/31183361 http://dx.doi.org/10.1155/2019/1395138 |
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