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Uncoupling Protein 2 Increases Blood Pressure in DJ‐1 Knockout Mice

BACKGROUND: The redox‐sensitive chaperone DJ‐1 and uncoupling protein 2 are protective against mitochondrial oxidative stress. We previously reported that renal‐selective depletion and germline deletion of DJ‐1 increases blood pressure in mice. This study aimed to determine the mechanisms involved i...

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Detalles Bibliográficos
Autores principales: De Miguel, Carmen, Hamrick, William C., Sedaka, Randee, Jagarlamudi, Sudha, Asico, Laureano D., Jose, Pedro A., Cuevas, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512091/
https://www.ncbi.nlm.nih.gov/pubmed/30995881
http://dx.doi.org/10.1161/JAHA.118.011856