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Defective Renal Angiotensin III and AT(2) Receptor Signaling in Prehypertensive Spontaneously Hypertensive Rats

BACKGROUND: Previous studies demonstrated that angiotensin (Ang) III, not Ang II, is the predominant endogenous agonist for Ang type‐2 receptor (AT (2)R)‐induced natriuresis in normal rats, and that hypertensive 12‐week‐old spontaneously hypertensive rats (SHR) lack natriuretic responses to Ang III....

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Detalles Bibliográficos
Autores principales:	Kemp, Brandon A., Howell, Nancy L., Keller, Susanna R., Gildea, John J., Shao, Weijian, Navar, Luis Gabriel, Carey, Robert M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512109/ https://www.ncbi.nlm.nih.gov/pubmed/31039659 http://dx.doi.org/10.1161/JAHA.119.012016

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