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RACHS‐ANZ: A Modified Risk Adjustment in Congenital Heart Surgery Model for Outcome Surveillance in Australia and New Zealand

BACKGROUND: Outcomes for pediatric cardiac surgery are commonly reported from international databases compiled from voluntary data submissions. Surgical outcomes for all children in a country or region are less commonly reported. We aimed to describe the bi‐national population‐based outcome for chil...

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Autores principales: McSharry, Brent, Straney, Lahn, Alexander, Janet, Gentles, Tom, Winlaw, David, Beca, John, Millar, Johnny, Shann, Frank, Wilkins, Barry, Numa, Andrew, Stocker, Christian, Erickson, Simon, Slater, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512128/
https://www.ncbi.nlm.nih.gov/pubmed/31039662
http://dx.doi.org/10.1161/JAHA.118.011390
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author McSharry, Brent
Straney, Lahn
Alexander, Janet
Gentles, Tom
Winlaw, David
Beca, John
Millar, Johnny
Shann, Frank
Wilkins, Barry
Numa, Andrew
Stocker, Christian
Erickson, Simon
Slater, Anthony
author_facet McSharry, Brent
Straney, Lahn
Alexander, Janet
Gentles, Tom
Winlaw, David
Beca, John
Millar, Johnny
Shann, Frank
Wilkins, Barry
Numa, Andrew
Stocker, Christian
Erickson, Simon
Slater, Anthony
author_sort McSharry, Brent
collection PubMed
description BACKGROUND: Outcomes for pediatric cardiac surgery are commonly reported from international databases compiled from voluntary data submissions. Surgical outcomes for all children in a country or region are less commonly reported. We aimed to describe the bi‐national population‐based outcome for children undergoing cardiac surgery in Australia and New Zealand and determine whether the Risk Adjustment for Congenital Heart Surgery (RACHS) classification could be used to create a model that accurately predicts in‐hospital mortality in this population. METHODS AND RESULTS: The study was conducted in all children's hospitals performing cardiac surgery in Australia and New Zealand between January 2007 and December 2015. The performance of the original RACHS‐1 model was assessed and compared with an alternative RACHS‐ANZ (Australia and New Zealand) model, developed balancing discrimination with parsimonious variable selection. A total of 14 324 hospital admissions were analyzed. The overall hospital mortality was 2.3%, ranging from 0.5% for RACHS category 1 procedures, to 17.0% for RACHS category 5 or 6 procedures. The original RACHS‐1 model was poorly calibrated with death overpredicted (1161 deaths predicted, 289 deaths observed). The RACHS‐ANZ model had better performance in this population with excellent discrimination (Az‐ROC of 0.830) and acceptable Hosmer and Lemeshow goodness‐of‐fit (P=0.216). CONCLUSIONS: The original RACHS‐1 model overpredicts mortality in children undergoing heart surgery in the current era. The RACHS‐ANZ model requires only 3 risk variables in addition to the RACHS procedure category, can be applied to a wider range of patients than RACHS‐1, and is suitable to use to monitor regional pediatric cardiac surgery outcomes.
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spelling pubmed-65121282019-05-20 RACHS‐ANZ: A Modified Risk Adjustment in Congenital Heart Surgery Model for Outcome Surveillance in Australia and New Zealand McSharry, Brent Straney, Lahn Alexander, Janet Gentles, Tom Winlaw, David Beca, John Millar, Johnny Shann, Frank Wilkins, Barry Numa, Andrew Stocker, Christian Erickson, Simon Slater, Anthony J Am Heart Assoc Original Research BACKGROUND: Outcomes for pediatric cardiac surgery are commonly reported from international databases compiled from voluntary data submissions. Surgical outcomes for all children in a country or region are less commonly reported. We aimed to describe the bi‐national population‐based outcome for children undergoing cardiac surgery in Australia and New Zealand and determine whether the Risk Adjustment for Congenital Heart Surgery (RACHS) classification could be used to create a model that accurately predicts in‐hospital mortality in this population. METHODS AND RESULTS: The study was conducted in all children's hospitals performing cardiac surgery in Australia and New Zealand between January 2007 and December 2015. The performance of the original RACHS‐1 model was assessed and compared with an alternative RACHS‐ANZ (Australia and New Zealand) model, developed balancing discrimination with parsimonious variable selection. A total of 14 324 hospital admissions were analyzed. The overall hospital mortality was 2.3%, ranging from 0.5% for RACHS category 1 procedures, to 17.0% for RACHS category 5 or 6 procedures. The original RACHS‐1 model was poorly calibrated with death overpredicted (1161 deaths predicted, 289 deaths observed). The RACHS‐ANZ model had better performance in this population with excellent discrimination (Az‐ROC of 0.830) and acceptable Hosmer and Lemeshow goodness‐of‐fit (P=0.216). CONCLUSIONS: The original RACHS‐1 model overpredicts mortality in children undergoing heart surgery in the current era. The RACHS‐ANZ model requires only 3 risk variables in addition to the RACHS procedure category, can be applied to a wider range of patients than RACHS‐1, and is suitable to use to monitor regional pediatric cardiac surgery outcomes. John Wiley and Sons Inc. 2019-05-01 /pmc/articles/PMC6512128/ /pubmed/31039662 http://dx.doi.org/10.1161/JAHA.118.011390 Text en © 2019 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Research
McSharry, Brent
Straney, Lahn
Alexander, Janet
Gentles, Tom
Winlaw, David
Beca, John
Millar, Johnny
Shann, Frank
Wilkins, Barry
Numa, Andrew
Stocker, Christian
Erickson, Simon
Slater, Anthony
RACHS‐ANZ: A Modified Risk Adjustment in Congenital Heart Surgery Model for Outcome Surveillance in Australia and New Zealand
title RACHS‐ANZ: A Modified Risk Adjustment in Congenital Heart Surgery Model for Outcome Surveillance in Australia and New Zealand
title_full RACHS‐ANZ: A Modified Risk Adjustment in Congenital Heart Surgery Model for Outcome Surveillance in Australia and New Zealand
title_fullStr RACHS‐ANZ: A Modified Risk Adjustment in Congenital Heart Surgery Model for Outcome Surveillance in Australia and New Zealand
title_full_unstemmed RACHS‐ANZ: A Modified Risk Adjustment in Congenital Heart Surgery Model for Outcome Surveillance in Australia and New Zealand
title_short RACHS‐ANZ: A Modified Risk Adjustment in Congenital Heart Surgery Model for Outcome Surveillance in Australia and New Zealand
title_sort rachs‐anz: a modified risk adjustment in congenital heart surgery model for outcome surveillance in australia and new zealand
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512128/
https://www.ncbi.nlm.nih.gov/pubmed/31039662
http://dx.doi.org/10.1161/JAHA.118.011390
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