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Association of Industry and Academic Sponsorship With Negative Phase 3 Oncology Trials and Reported Outcomes on Participant Survival: A Pooled Analysis
IMPORTANCE: Only 3.4% of cancer drugs evaluated in phase 1 trials are approved by the US Food and Drug Administration, with most failing in phase 3 trials. OBJECTIVE: To investigate whether an association exists between the sponsorship and conduct of a negative phase 3 randomized clinical trial (RCT...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Medical Association
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512293/ https://www.ncbi.nlm.nih.gov/pubmed/31074821 http://dx.doi.org/10.1001/jamanetworkopen.2019.3684 |