Cargando…

Preventing disability in older adults with mild cognitive impairment: A Strategy Training intervention study

Non-pharmacological interventions designed to change cognitive function in older adults with Mild Cognitive Impairment have shown mixed results. Few studied interventions directly address preclinical disability. Slowing changes in disability are critical preserve independence and health related qual...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodakowski, Juleen, Golias, Katlyn W., Reynolds, Charles F., Butters, Meryl A., Lopez, Oscar L., Dew, Mary Amanda, Skidmore, Elizabeth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512744/
https://www.ncbi.nlm.nih.gov/pubmed/31111114
http://dx.doi.org/10.1016/j.conctc.2019.100368
_version_ 1783417691850145792
author Rodakowski, Juleen
Golias, Katlyn W.
Reynolds, Charles F.
Butters, Meryl A.
Lopez, Oscar L.
Dew, Mary Amanda
Skidmore, Elizabeth R.
author_facet Rodakowski, Juleen
Golias, Katlyn W.
Reynolds, Charles F.
Butters, Meryl A.
Lopez, Oscar L.
Dew, Mary Amanda
Skidmore, Elizabeth R.
author_sort Rodakowski, Juleen
collection PubMed
description Non-pharmacological interventions designed to change cognitive function in older adults with Mild Cognitive Impairment have shown mixed results. Few studied interventions directly address preclinical disability. Slowing changes in disability are critical preserve independence and health related quality of life in older adults with Mild Cognitive Impairment. In this study, we discuss the design of the trial, challenges encountered, and solutions generated to guide future trials designed to prevent the onset of disability among at-risk older adults. We compared Strategy Training to enhanced-usual care in 30 older adults with Mild Cognitive Impairment. We recruited 79.7% (n = 188) of the potential participants through direct-to-consumer recruitment. We refined a three-step screening process, including a phone screen, initial in-person screening, and full in-person screening. This screening processes resulted in a high percentage of older adults completing the neuropsychological battery and adjudication of Mild Cognitive Impairment. Conducting a disability prevention among individuals without overt disability is a novel approach. Nevertheless, one of the greatest limitations to our project is the fact that follow-up is restricted to 1 year. Findings from this study can inform the design and conduct of future clinical trials that seek to slow progression of disability in older adults with Mild Cognitive Impairment.
format Online
Article
Text
id pubmed-6512744
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-65127442019-05-20 Preventing disability in older adults with mild cognitive impairment: A Strategy Training intervention study Rodakowski, Juleen Golias, Katlyn W. Reynolds, Charles F. Butters, Meryl A. Lopez, Oscar L. Dew, Mary Amanda Skidmore, Elizabeth R. Contemp Clin Trials Commun Article Non-pharmacological interventions designed to change cognitive function in older adults with Mild Cognitive Impairment have shown mixed results. Few studied interventions directly address preclinical disability. Slowing changes in disability are critical preserve independence and health related quality of life in older adults with Mild Cognitive Impairment. In this study, we discuss the design of the trial, challenges encountered, and solutions generated to guide future trials designed to prevent the onset of disability among at-risk older adults. We compared Strategy Training to enhanced-usual care in 30 older adults with Mild Cognitive Impairment. We recruited 79.7% (n = 188) of the potential participants through direct-to-consumer recruitment. We refined a three-step screening process, including a phone screen, initial in-person screening, and full in-person screening. This screening processes resulted in a high percentage of older adults completing the neuropsychological battery and adjudication of Mild Cognitive Impairment. Conducting a disability prevention among individuals without overt disability is a novel approach. Nevertheless, one of the greatest limitations to our project is the fact that follow-up is restricted to 1 year. Findings from this study can inform the design and conduct of future clinical trials that seek to slow progression of disability in older adults with Mild Cognitive Impairment. Elsevier 2019-05-01 /pmc/articles/PMC6512744/ /pubmed/31111114 http://dx.doi.org/10.1016/j.conctc.2019.100368 Text en © 2019 The Authors. Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Rodakowski, Juleen
Golias, Katlyn W.
Reynolds, Charles F.
Butters, Meryl A.
Lopez, Oscar L.
Dew, Mary Amanda
Skidmore, Elizabeth R.
Preventing disability in older adults with mild cognitive impairment: A Strategy Training intervention study
title Preventing disability in older adults with mild cognitive impairment: A Strategy Training intervention study
title_full Preventing disability in older adults with mild cognitive impairment: A Strategy Training intervention study
title_fullStr Preventing disability in older adults with mild cognitive impairment: A Strategy Training intervention study
title_full_unstemmed Preventing disability in older adults with mild cognitive impairment: A Strategy Training intervention study
title_short Preventing disability in older adults with mild cognitive impairment: A Strategy Training intervention study
title_sort preventing disability in older adults with mild cognitive impairment: a strategy training intervention study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512744/
https://www.ncbi.nlm.nih.gov/pubmed/31111114
http://dx.doi.org/10.1016/j.conctc.2019.100368
work_keys_str_mv AT rodakowskijuleen preventingdisabilityinolderadultswithmildcognitiveimpairmentastrategytraininginterventionstudy
AT goliaskatlynw preventingdisabilityinolderadultswithmildcognitiveimpairmentastrategytraininginterventionstudy
AT reynoldscharlesf preventingdisabilityinolderadultswithmildcognitiveimpairmentastrategytraininginterventionstudy
AT buttersmeryla preventingdisabilityinolderadultswithmildcognitiveimpairmentastrategytraininginterventionstudy
AT lopezoscarl preventingdisabilityinolderadultswithmildcognitiveimpairmentastrategytraininginterventionstudy
AT dewmaryamanda preventingdisabilityinolderadultswithmildcognitiveimpairmentastrategytraininginterventionstudy
AT skidmoreelizabethr preventingdisabilityinolderadultswithmildcognitiveimpairmentastrategytraininginterventionstudy