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Formulation and evaluation of simvastatin polymeric nanoparticles loaded in hydrogel for optimum wound healing purpose

PURPOSE: The aim of this study was to formulate a hydrogel loaded with polymeric nanoparticles (PoNPs) of simvastatin (SIM) for topical wound healing application. MATERIALS AND METHODS: The SIM PoNPs were prepared by using the nanoprecipitation method to improve the drug solubility and skin permeati...

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Detalles Bibliográficos
Autores principales:	Farghaly Aly, Usama, Abou-Taleb, Heba A, Abdellatif, Ahmed AH, Sameh Tolba, Nahla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512793/ https://www.ncbi.nlm.nih.gov/pubmed/31190737 http://dx.doi.org/10.2147/DDDT.S198413

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