Cargando…

6,7-Dihydroxy-2-(4′-hydroxyphenyl)naphthalene induces HCT116 cell apoptosis through activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway

BACKGROUND: Colorectal cancer is the third leading cause of cancer-related deaths worldwide, and therefore, the development of novel drugs for its prevention and therapy are urgently required. This study aimed to determine the molecular mechanism of 6,7-dihydroxy-2-(4′-hydroxyphenyl) naphthalene (PN...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chiu, Ching-Feng, Lai, Guan-Ying, Chen, Chung-Hwan, Chiu, Chien-Chao, Hung, Shao-Wen, Chang, Chi-Fen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512798/ https://www.ncbi.nlm.nih.gov/pubmed/31190740 http://dx.doi.org/10.2147/DDDT.S193914

Ejemplares similares

Benzyltributylammonium 6,7-dihydroxynaphthalene-2-sulfonate
por: Uta, Kazuya, et al.
Publicado: (2009)

Knockout of MARCH2 inhibits the growth of HCT116 colon cancer cells by inducing endoplasmic reticulum stress
por: Xia, Dan, et al.
Publicado: (2017)

Cryptotanshinone Inhibits the Growth of HCT116 Colorectal Cancer Cells Through Endoplasmic Reticulum Stress-Mediated Autophagy
por: Fu, Xiaojing, et al.
Publicado: (2021)

Faecalibacterium prausnitzii Ameliorates Colorectal Tumorigenesis and Suppresses Proliferation of HCT116 Colorectal Cancer Cells
por: Dikeocha, Ifeoma Julieth, et al.
Publicado: (2022)

Cytotoxic and apoptotic potential of gemini-chrysophanol nanoparticles against human colorectal cancer HCT-116 cell lines
por: Naqishbandi, Alaadin M.
Publicado: (2022)

Activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway in human lung cancer cells by the new synthetic flavonoid, LZ-205
por: Zhang, Yi, et al.
Publicado: (2016)

Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells
por: Phang, Chung-Weng, et al.
Publicado: (2016)

Graphene Oxide Nanosurface Reduces Apoptotic Death of HCT116 Colon Carcinoma Cells Induced by Zirconium Trisulfide Nanoribbons
por: Tatarskiy, Victor V., et al.
Publicado: (2023)

miRNA-mRNA Regulatory Network Reveals miRNAs in HCT116 in Response to Folic Acid Deficiency via Regulating Vital Genes of Endoplasmic Reticulum Stress Pathway
por: Lu, Lin, et al.
Publicado: (2021)

Intra-Tumoral Heterogeneity in Metastatic Potential and Survival Signaling between Iso-Clonal HCT116 and HCT116b Human Colon Carcinoma Cell Lines
por: Chowdhury, Sanjib, et al.
Publicado: (2013)

Cytotoxic and Apoptotic Activity of Aglaforbesin Derivative Isolated from Aglaia loheri Merr. on HCT116 Human Colorectal Cancer Cells
por: Abalos, Norielyn N., et al.
Publicado: (2021)

Bursopentin (BP5) induces G1 phase cell cycle arrest and endoplasmic reticulum stress/mitochondria-mediated caspase-dependent apoptosis in human colon cancer HCT116 cells
por: Li, Jing, et al.
Publicado: (2019)

Benzyltributylammonium 4,6-dihydroxynaphthalene-2-sulfonate
por: Uta, Kazuya, et al.
Publicado: (2009)

The apoptotic response in HCT116(BAX-/- )cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein
por: Semaan, Sheila J, et al.
Publicado: (2010)

Resistin and Visfatin Expression in HCT-116 Colorectal Cancer Cell Line
por: Ghaemmaghami, Sara, et al.
Publicado: (2013)

Characterization of sphere-forming HCT116 clones by whole RNA sequencing
por: Chung, Eunkyung, et al.
Publicado: (2016)

Procaine Induces Epigenetic Changes in HCT116 Colon Cancer Cells
por: Sabit, Hussein, et al.
Publicado: (2016)

Entrainment of superoxide rhythm by menadione in HCT116 colon cancer cells
por: Kizhuveetil, Uma, et al.
Publicado: (2019)

Activations of Both Extrinsic and Intrinsic Pathways in HCT 116 Human Colorectal Cancer Cells Contribute to Apoptosis through p53-Mediated ATM/Fas Signaling by Emilia sonchifolia Extract, a Folklore Medicinal Plant
por: Lan, Yu-Hsuan, et al.
Publicado: (2012)

Antimicrobial peptide FF/CAP18 induces apoptotic cell death in HCT116 colon cancer cells via changes in the metabolic profile
por: KURODA, KENGO, et al.
Publicado: (2015)

ROS-induced cleavage of NHLRC2 by caspase-8 leads to apoptotic cell death in the HCT116 human colon cancer cell line
por: Nishi, Kensuke, et al.
Publicado: (2017)

1-(3,4-Dihydroxyphenyl)-2-(4-hydroxyphenyl)ethanone
por: Xiao, Zhu-Ping, et al.
Publicado: (2009)

Antichemosensitizing effect of resveratrol in cotreatment with oxaliplatin in HCT116 colon cancer cell
por: Park, Dong-Guk
Publicado: (2014)

Carvacrol alters soluble factors in HCT-116 and HT-29 cell lines
por: PAKDEMİRLİ, Ahu, et al.
Publicado: (2020)

Exploring the Apoptotic-Induced Biochemical Mechanism of Traditional Thai Herb (Kerra™) Extract in HCT116 Cells Using a Label-Free Proteomics Approach
por: Siriwaseree, Jeeraprapa, et al.
Publicado: (2023)

Fulvic Acid Attenuates Resistin-Induced Adhesion of HCT-116 Colorectal Cancer Cells to Endothelial Cells
por: Huang, Wen-Shih, et al.
Publicado: (2015)

NMS-873 Leads to Dysfunctional Glycometabolism in A p97-Independent Manner in HCT116 Colon Cancer Cells
por: Li, Shan, et al.
Publicado: (2022)

Src-FAK Signaling Mediates Interleukin 6-Induced HCT116 Colorectal Cancer Epithelial–Mesenchymal Transition
por: Huang, Yu-Han, et al.
Publicado: (2023)

Change in Expression of Survivin Caused by Using Oxaliplatin in HCT116 Colon Cancer Cells
por: Sohn, Won Jun, et al.
Publicado: (2010)

In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line
por: Wang, Jigang, et al.
Publicado: (2016)

Evodiamine Induces Apoptosis and Inhibits Migration of HCT-116 Human Colorectal Cancer Cells
por: Zhao, Lv-Cui, et al.
Publicado: (2015)

DZNep inhibits the proliferation of colon cancer HCT116 cells by inducing senescence and apoptosis
por: Sha, Mingquan, et al.
Publicado: (2015)

Methylsulfonylmethane Induces p53 Independent Apoptosis in HCT-116 Colon Cancer Cells
por: Karabay, Arzu Zeynep, et al.
Publicado: (2016)

Zerumbone reduces proliferation of HCT116 colon cancer cells by inhibition of TNF-alpha
por: Singh, Salam Pradeep, et al.
Publicado: (2018)

Proteins that interact with calgranulin B in the human colon cancer cell line HCT-116
por: Myung, Jae Kyung, et al.
Publicado: (2016)

In vivo anticancer activity of a rhodium metalloinsertor in the HCT116 xenograft tumor model
por: Threatt, Stephanie D., et al.
Publicado: (2020)

Oligo-Fucoidan Prevents M2 Macrophage Differentiation and HCT116 Tumor Progression
por: Chen, Li-Mei, et al.
Publicado: (2020)

A zebrafish HCT116 xenograft model to predict anandamide outcomes on colorectal cancer
por: Maradonna, Francesca, et al.
Publicado: (2022)

Bufalin Inhibits HCT116 Colon Cancer Cells and Its Orthotopic Xenograft Tumor in Mice Model through Genes Related to Apoptotic and PTEN/AKT Pathways
por: Wang, Jie, et al.
Publicado: (2015)

Aurora kinase A inhibitor TCS7010 demonstrates pro-apoptotic effect through the unfolded protein response pathway in HCT116 colon cancer cells
por: Lee, Da Hyun, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_a6c5um6n0823d47q4png1sj4ff