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Tracking tumor evolution one-cell-at-a-time
Accumulating evidence suggests that intra-tumor heterogeneity (ITH) within tumor sub-populations is a major contributor to therapy resistance, with genomically distinct clonal populations exhibiting different therapeutic vulnerabilities. Here we employed single-cell transcriptomics in patient-derive...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512908/ https://www.ncbi.nlm.nih.gov/pubmed/31131309 http://dx.doi.org/10.1080/23723556.2019.1590089 |