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ALTHEA Gold Libraries™: antibody libraries for therapeutic antibody discovery

We describe here the design, construction and validation of ALTHEA Gold Libraries™. These single-chain variable fragment (scFv), semisynthetic libraries are built on synthetic human well-known IGHV and IGKV germline genes combined with natural human complementarity-determining region (CDR)-H3/J(H) (...

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Detalles Bibliográficos
Autores principales:	Valadon, Philippe, Pérez-Tapia, Sonia M., Nelson, Renae S., Guzmán-Bringas, Omar U., Arrieta-Oliva, Hugo I., Gómez-Castellano, Keyla M., Pohl, Mary Ann, Almagro, Juan C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512909/ https://www.ncbi.nlm.nih.gov/pubmed/30663541 http://dx.doi.org/10.1080/19420862.2019.1571879

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