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Capture and display of antibodies secreted by hybridoma cells enables fluorescent on-cell screening
Hybridoma methods for monoclonal antibody (mAb) cloning are a mainstay of biomedical research, but they are hindered by the need to maintain hybridomas in oligoclonal pools during antibody screening. Here, we describe a system in which hybridomas specifically capture and display the mAbs they secret...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512912/ https://www.ncbi.nlm.nih.gov/pubmed/30794061 http://dx.doi.org/10.1080/19420862.2019.1574520 |