Nuclear transcriptional regulation by mitochondrial-encoded MOTS-c

Cellular stress response is coordinated through the communication between mitochondria and the nucleus. However, whereas mitochondria are regulated by nuclear-encoded proteins, the nucleus was considered ungoverned by mitochondrial-encoded factors. We recently reported that a mitochondrial-encoded p...

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Detalles Bibliográficos
Autor principal: Lee, Changhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Author's Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512917/
https://www.ncbi.nlm.nih.gov/pubmed/31131297
http://dx.doi.org/10.1080/23723556.2018.1549464
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author Lee, Changhan
author_facet Lee, Changhan
author_sort Lee, Changhan
collection PubMed
description Cellular stress response is coordinated through the communication between mitochondria and the nucleus. However, whereas mitochondria are regulated by nuclear-encoded proteins, the nucleus was considered ungoverned by mitochondrial-encoded factors. We recently reported that a mitochondrial-encoded peptide directly regulates the nuclear genome upon cellular stress, indicating an integrated bi-genomic cross-communication mechanism.
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spelling pubmed-65129172020-02-15 Nuclear transcriptional regulation by mitochondrial-encoded MOTS-c Lee, Changhan Mol Cell Oncol Author's Views Cellular stress response is coordinated through the communication between mitochondria and the nucleus. However, whereas mitochondria are regulated by nuclear-encoded proteins, the nucleus was considered ungoverned by mitochondrial-encoded factors. We recently reported that a mitochondrial-encoded peptide directly regulates the nuclear genome upon cellular stress, indicating an integrated bi-genomic cross-communication mechanism. Taylor & Francis 2019-02-15 /pmc/articles/PMC6512917/ /pubmed/31131297 http://dx.doi.org/10.1080/23723556.2018.1549464 Text en © 2019 The Author(s). Published with license by Taylor & Francis Group, LLC. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Author's Views
Lee, Changhan
Nuclear transcriptional regulation by mitochondrial-encoded MOTS-c
title Nuclear transcriptional regulation by mitochondrial-encoded MOTS-c
title_full Nuclear transcriptional regulation by mitochondrial-encoded MOTS-c
title_fullStr Nuclear transcriptional regulation by mitochondrial-encoded MOTS-c
title_full_unstemmed Nuclear transcriptional regulation by mitochondrial-encoded MOTS-c
title_short Nuclear transcriptional regulation by mitochondrial-encoded MOTS-c
title_sort nuclear transcriptional regulation by mitochondrial-encoded mots-c
topic Author's Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512917/
https://www.ncbi.nlm.nih.gov/pubmed/31131297
http://dx.doi.org/10.1080/23723556.2018.1549464
work_keys_str_mv AT leechanghan nucleartranscriptionalregulationbymitochondrialencodedmotsc

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