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Mechano-regulation of proline metabolism and cancer progression by kindlin-2
Alterations of cell mechano-environment and metabolism are common features of malignant neoplasm. We recently showed that increased stiffness of extracellular matrix is intrinsically linked to up-regulation of proline synthesis through a mechano-responsive fermitin family homolog 2 (FERMT2, best kno...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512932/ https://www.ncbi.nlm.nih.gov/pubmed/31131313 http://dx.doi.org/10.1080/23723556.2019.1596003 |