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Emerging Evidence of Chromosome Folding by Loop Extrusion

Chromosome organization poses a remarkable physical problem with many biological consequences: How can molecular interactions between proteins at the nanometer scale organize micron-long chromatinized DNA molecules, insulating or facilitating interactions between specific genomic elements? The mecha...

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Detalles Bibliográficos
Autores principales:	Fudenberg, Geoffrey, Abdennur, Nezar, Imakaev, Maxim, Goloborodko, Anton, Mirny, Leonid A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512960/ https://www.ncbi.nlm.nih.gov/pubmed/29728444 http://dx.doi.org/10.1101/sqb.2017.82.034710

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