STAT2 dependent Type I Interferon response promotes dysbiosis and luminal expansion of the enteric pathogen Salmonella Typhimurium

The mechanisms by which the gut luminal environment is disturbed by the immune system to foster pathogenic bacterial growth and survival remain incompletely understood. Here, we show that STAT2 dependent type I IFN signaling contributes to the inflammatory environment by disrupting hypoxia enabling...

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Detalles Bibliográficos
Autores principales: Wilson, R. Paul, Tursi, Sarah A., Rapsinski, Glenn J., Medeiros, Nicole J., Le, Long S., Kotredes, Kevin P., Patel, Sajan, Liverani, Elisabetta, Sun, Shuang, Zhu, Wenhan, Kilpatrick, Laurie, Winter, Sebastian E., Gamero, Ana M., Tükel, Çagla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513112/
https://www.ncbi.nlm.nih.gov/pubmed/31009517
http://dx.doi.org/10.1371/journal.ppat.1007745

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