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Synthesis and Statistical Optimization of Poly (Lactic-Co-Glycolic Acid) Nanoparticles Encapsulating GLP1 Analog Designed for Oral Delivery
PURPOSE: To design and stabilize Liraglutide loaded poly (lactic-co-glycolic acid) nanoparticles (PLGA NPs) proper for oral administration. METHODS: PLGA NPs were prepared by means of double emulsion solvent evaporation method and optimized by applying 7-factor 2-level Plackett-Burman screening desi...
Autores principales: | Ismail, Ruba, Sovány, Tamás, Gácsi, Attila, Ambrus, Rita, Katona, Gábor, Imre, Norbert, Csóka, Ildikó |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513835/ https://www.ncbi.nlm.nih.gov/pubmed/31087188 http://dx.doi.org/10.1007/s11095-019-2620-9 |
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