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The importance of inter-individual Kupffer cell variability in the governance of hepatic toxicity in a 3D primary human liver microtissue model

The potential for nanomaterial (NM) translocation to secondary organs is a realistic prospect, with the liver one of the most important target organs. Traditional in vitro or ex vivo hepatic toxicology models are often limiting and/or troublesome (i.e. short life-span reduced metabolic activity, lac...

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Detalles Bibliográficos
Autores principales: Kermanizadeh, Ali, Brown, David M., Moritz, Wolfgang, Stone, Vicki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513945/
https://www.ncbi.nlm.nih.gov/pubmed/31086251
http://dx.doi.org/10.1038/s41598-019-43870-8