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Opposite Profiles of Complement in Antiphospholipid Syndrome (APS) and Systemic Lupus Erythematosus (SLE) Among Patients With Antiphospholipid Antibodies (aPL)
APS is the association of antiphospholipid antibodies (aPL) with thromboses and/or recurrent pregnancy loss (RPL). Among patients with SLE, one-third have aPL and 10–15% have a manifestation of secondary APS. Animal studies suggested that complement activation plays an important role in the pathogen...
Autores principales: | Savelli, Stephanie L., Roubey, Robert A. S., Kitzmiller, Kathryn J., Zhou, Danlei, Nagaraja, Haikady N., Mulvihill, Evan, Barbar-Smiley, Fatima, Ardoin, Stacy P., Wu, Yee Ling, Yu, Chack-Yung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514053/ https://www.ncbi.nlm.nih.gov/pubmed/31134052 http://dx.doi.org/10.3389/fimmu.2019.00885 |
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