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An Extension of the Kimura Two-Parameter Model to the Natural Evolutionary Process
Accurate estimates of genetic difference are required for research in evolutionary biology. Here we extend the Kimura two-parameter (K2P) model by considering gaps (insertions and/or deletions) and introduce a new measure for estimating genetic difference between two nucleotide sequences in terms of...
Autores principales: | Nishimaki, Takuma, Sato, Keiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514111/ https://www.ncbi.nlm.nih.gov/pubmed/30631891 http://dx.doi.org/10.1007/s00239-018-9885-1 |
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