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Biological Applications of Organic Electrochemical Transistors: Electrochemical Biosensors and Electrophysiology Recording

Organic electrochemical transistors (OECTs) are recently developed high-efficient transducers not only for electrochemical biosensor but also for cell electrophysiological recording due to the separation of gate electrode from the transistor device. The efficient integration of OECTs with electroche...

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Detalles Bibliográficos
Autores principales: Bai, Liming, Elósegui, Cristina García, Li, Weiqi, Yu, Ping, Fei, Junjie, Mao, Lanqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514146/
https://www.ncbi.nlm.nih.gov/pubmed/31134185
http://dx.doi.org/10.3389/fchem.2019.00313
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author Bai, Liming
Elósegui, Cristina García
Li, Weiqi
Yu, Ping
Fei, Junjie
Mao, Lanqun
author_facet Bai, Liming
Elósegui, Cristina García
Li, Weiqi
Yu, Ping
Fei, Junjie
Mao, Lanqun
author_sort Bai, Liming
collection PubMed
description Organic electrochemical transistors (OECTs) are recently developed high-efficient transducers not only for electrochemical biosensor but also for cell electrophysiological recording due to the separation of gate electrode from the transistor device. The efficient integration of OECTs with electrochemical gate electrode makes the as-prepared sensors with improved performance, such as sensitivity, limit of detection, and selectivity. We herein reviewed the recent progress of OECTs-based biosensors and cell electrophysiology recording, mainly focusing on the principle and chemical design of gate electrode and the channel. First, the configuration, work principle, semiconductor of OECT are briefly introduced. Then different kinds of sensing modes are reviewed, especially for the biosensing and electrophysiological recording. Finally, the challenges and opportunities of this research field are discussed.
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spelling pubmed-65141462019-05-27 Biological Applications of Organic Electrochemical Transistors: Electrochemical Biosensors and Electrophysiology Recording Bai, Liming Elósegui, Cristina García Li, Weiqi Yu, Ping Fei, Junjie Mao, Lanqun Front Chem Chemistry Organic electrochemical transistors (OECTs) are recently developed high-efficient transducers not only for electrochemical biosensor but also for cell electrophysiological recording due to the separation of gate electrode from the transistor device. The efficient integration of OECTs with electrochemical gate electrode makes the as-prepared sensors with improved performance, such as sensitivity, limit of detection, and selectivity. We herein reviewed the recent progress of OECTs-based biosensors and cell electrophysiology recording, mainly focusing on the principle and chemical design of gate electrode and the channel. First, the configuration, work principle, semiconductor of OECT are briefly introduced. Then different kinds of sensing modes are reviewed, especially for the biosensing and electrophysiological recording. Finally, the challenges and opportunities of this research field are discussed. Frontiers Media S.A. 2019-05-07 /pmc/articles/PMC6514146/ /pubmed/31134185 http://dx.doi.org/10.3389/fchem.2019.00313 Text en Copyright © 2019 Bai, Elósegui, Li, Yu, Fei and Mao. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Bai, Liming
Elósegui, Cristina García
Li, Weiqi
Yu, Ping
Fei, Junjie
Mao, Lanqun
Biological Applications of Organic Electrochemical Transistors: Electrochemical Biosensors and Electrophysiology Recording
title Biological Applications of Organic Electrochemical Transistors: Electrochemical Biosensors and Electrophysiology Recording
title_full Biological Applications of Organic Electrochemical Transistors: Electrochemical Biosensors and Electrophysiology Recording
title_fullStr Biological Applications of Organic Electrochemical Transistors: Electrochemical Biosensors and Electrophysiology Recording
title_full_unstemmed Biological Applications of Organic Electrochemical Transistors: Electrochemical Biosensors and Electrophysiology Recording
title_short Biological Applications of Organic Electrochemical Transistors: Electrochemical Biosensors and Electrophysiology Recording
title_sort biological applications of organic electrochemical transistors: electrochemical biosensors and electrophysiology recording
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514146/
https://www.ncbi.nlm.nih.gov/pubmed/31134185
http://dx.doi.org/10.3389/fchem.2019.00313
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