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20(S)-Protopanaxadiol Inhibits Angiotensin II-Induced Epithelial- Mesenchymal Transition by Downregulating SIRT1

20(S)-Protopanaxadiol (PPD) is one of the major active metabolites in ginseng saponin. Our previous studies revealed a broad spectrum of antitumor effects of PPD. Angiotensin II (Ang II), the biologically active peptide of the renin-angiotensin system (RAS), plays a critical role in the metastasis o...

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Detalles Bibliográficos
Autores principales: Wang, Yuchen, Xu, Huali, Fu, Wenwen, Lu, Zeyuan, Guo, Minyu, Wu, Xueji, Sun, Mingyang, Liu, Yanzhe, Yu, Xiaofeng, Sui, Dayun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514190/
https://www.ncbi.nlm.nih.gov/pubmed/31133857
http://dx.doi.org/10.3389/fphar.2019.00475