Cargando…

Long Non-coding RNA CASC2 Enhances the Antitumor Activity of Cisplatin Through Suppressing the Akt Pathway by Inhibition of miR-181a in Esophageal Squamous Cell Carcinoma Cells

Background: Long non-coding RNA CASC2 (lncRNA CASC2) has been found to be down-regulated in esophageal squamous cell carcinoma (ESCC). However, the effect of CASC2 on cisplatin-treated ESCC was unclear. The present study aimed to evaluate the role of CASC2 in cisplatin-treated ESCC cells. Methods: T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Dengyan, Yu, Yang, Qi, Yu, Wu, Kai, Liu, Donglei, Yang, Yang, Zhang, Chunyang, Zhao, Song
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514198/ https://www.ncbi.nlm.nih.gov/pubmed/31134151 http://dx.doi.org/10.3389/fonc.2019.00350

Ejemplares similares

Proteasome inhibitor MG132 inhibits the proliferation and promotes the cisplatin-induced apoptosis of human esophageal squamous cell carcinoma cells
por: DANG, LIFENG, et al.
Publicado: (2014)

Silencing of histone deacetylase 3 suppresses the development of esophageal squamous cell carcinoma through regulation of miR-494-mediated TGIF1
por: Yang, Yang, et al.
Publicado: (2022)

Effect of YAP1 silencing on esophageal cancer
por: Zhao, Jia, et al.
Publicado: (2016)

PAR1 and PAR4 exert opposite effects on tumor growth and metastasis of esophageal squamous cell carcinoma via STAT3 and NF-κB signaling pathways
por: Zhao, Jia, et al.
Publicado: (2021)

Long noncoding RNA PART1 promotes progression of non‐small cell lung cancer cells via JAK‐STAT signaling pathway
por: Zhu, Dengyan, et al.
Publicado: (2019)

Upregulation of the long non-coding RNA CASC9 as a biomarker for squamous cell carcinoma
por: Sassenberg, Madeleine, et al.
Publicado: (2019)

Overexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma
por: Zhang, Qingyi, et al.
Publicado: (2019)

MicroRNA let-7i Inhibits Histone Lysine Demethylase KDM5B to Halt Esophageal Cancer Progression
por: Yang, Yang, et al.
Publicado: (2020)

miRNA-181a-5p Enhances the Sensitivity of Cells to Cisplatin in Esophageal Adenocarcinoma by Targeting CBLB
por: Yang, Song, et al.
Publicado: (2020)

Raltitrexed Enhances the Antitumor Effect of Apatinib in Human Esophageal Squamous Carcinoma Cells via Akt and Erk Pathways
por: Zhen, Hongchao, et al.
Publicado: (2020)

Long non-coding RNA CASC2 suppresses epithelial-mesenchymal transition of hepatocellular carcinoma cells through CASC2/miR-367/FBXW7 axis
por: Wang, Yufeng, et al.
Publicado: (2017)

Long noncoding RNA CASC2 suppresses esophageal squamous cell carcinoma progression by increasing SOCS1 expression
por: Sun, Ke, et al.
Publicado: (2019)

MiR-495 inhibits esophageal squamous cell carcinoma progression by targeting Akt1
por: Mao, Yu, et al.
Publicado: (2016)

Long non-coding RNA CASC15 facilitates esophageal squamous cell carcinoma tumorigenesis via decreasing SIM2 stability via FTO-mediated demethylation
por: Qin, Bo, et al.
Publicado: (2021)

miR-218 suppresses tumor growth and enhances the chemosensitivity of esophageal squamous cell carcinoma to cisplatin
por: Tian, Hang, et al.
Publicado: (2022)

miR-145 sensitizes esophageal squamous cell carcinoma to cisplatin through directly inhibiting PI3K/AKT signaling pathway
por: Zheng, Tian-Liang, et al.
Publicado: (2019)

The m6A-induced lncRNA CASC8 promotes proliferation and chemoresistance via upregulation of hnRNPL in esophageal squamous cell carcinoma
por: Wu, Qingnan, et al.
Publicado: (2022)

Long non‐coding RNA CASC7 is associated with the pathogenesis of heart failure via modulating the expression of miR‐30c
por: Xu, Yu‐li, et al.
Publicado: (2020)

Increased expression of lncRNA CASC9 promotes tumor progression by suppressing autophagy-mediated cell apoptosis via the AKT/mTOR pathway in oral squamous cell carcinoma
por: Yang, Yixin, et al.
Publicado: (2019)

The Long Non-Coding RNA CASC2 Suppresses Cell Viability, Migration, and Invasion in Hepatocellular Carcinoma Cells by Directly Downregulating miR-183
por: Sun, Jian, et al.
Publicado: (2019)

Long non-coding RNA CASC2 enhanced cisplatin-induced viability inhibition of non-small cell lung cancer cells by regulating the PTEN/PI3K/Akt pathway through down-regulation of miR-18a and miR-21
por: Li, Li, et al.
Publicado: (2018)

LncRNA CASC9 promotes esophageal squamous cell carcinoma metastasis through upregulating LAMC2 expression by interacting with the CREB-binding protein
por: Liang, Yan, et al.
Publicado: (2018)

Long non-coding RNA CASC15 is upregulated in hepatocellular carcinoma and facilitates hepatocarcinogenesis
por: He, Tianyu, et al.
Publicado: (2017)

Long non‐coding RNA CASC8 polymorphisms are associated with the risk of esophageal cancer in a Chinese population
por: Sang, Yonghua, et al.
Publicado: (2020)

Up-regulation of lncRNA CASC9 promotes esophageal squamous cell carcinoma growth by negatively regulating PDCD4 expression through EZH2
por: Wu, Yuanyuan, et al.
Publicado: (2017)

miR-181b inhibits chemoresistance in cisplatin-resistant H446 small cell lung cancer cells by targeting Bcl-2
por: Liu, Hui-Ning, et al.
Publicado: (2018)

Targeting MCL-1 sensitizes human esophageal squamous cell carcinoma cells to cisplatin-induced apoptosis
por: Yu, Xinfang, et al.
Publicado: (2017)

Activation of PPARγ suppresses proliferation and induces apoptosis of esophageal cancer cells by inhibiting TLR4-dependent MAPK pathway
por: Wu, Kai, et al.
Publicado: (2016)

Long non-coding RNA CASC2 serves as a ceRNA of microRNA-21 to promote PDCD4 expression in oral squamous cell carcinoma
por: Pan, Lina, et al.
Publicado: (2019)

DASES: a database of alternative splicing for esophageal squamous cell carcinoma
por: Chen, Yilong, et al.
Publicado: (2023)

Association between RNF2+P-AKT expression in pretreatment biopsy specimens, and poor survival following radiotherapy in patients with esophageal squamous cell carcinoma
por: Li, Qiaofang, et al.
Publicado: (2019)

Long non-coding RNA CASC2 upregulates PTEN to suppress pancreatic carcinoma cell metastasis by downregulating miR-21
por: Zhang, Hui, et al.
Publicado: (2019)

miR-181 regulates cisplatin-resistant non-small cell lung cancer via downregulation of autophagy through the PTEN/PI3K/AKT pathway
por: Liu, Jiangang, et al.
Publicado: (2018)

Dihydroartemisinin Sensitizes Esophageal Squamous Cell Carcinoma to Cisplatin by Inhibiting Sonic Hedgehog Signaling
por: Cui, Wei, et al.
Publicado: (2020)

Long non‐coding RNA GAS5 is induced by interferons and plays an antitumor role in esophageal squamous cell carcinoma
por: Huang, Jianbing, et al.
Publicado: (2018)

Targeted Inhibition of mTOR Signaling Improves Sensitivity of Esophageal Squamous Cell Carcinoma Cells to Cisplatin
por: Hou, Guiqin, et al.
Publicado: (2014)

miR-181d promotes cell proliferation via the IGF1/PI3K/AKT axis in glioma
por: Tang, Dong, et al.
Publicado: (2020)

Screening and identification of miR-181a-5p in oral squamous cell carcinoma and functional verification in vivo and in vitro
por: Xu, Guoqiang, et al.
Publicado: (2023)

An integrated analysis of dysregulated SCD1 in human cancers and functional verification of miR-181a-5p/SCD1 axis in esophageal squamous cell carcinoma
por: Wang, Bing-Yen, et al.
Publicado: (2023)

LncRNA CASC15 upregulates cyclin D1 by downregulating miR-365 in laryngeal squamous cell carcinoma to promote cell proliferation
por: Zhu, Minhui, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_g114i2itb05u913s71ufkb1nlh