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PBRM1 Regulates Stress Response in Epithelial Cells
Polybromo1 (PBRM1) is a chromatin remodeler subunit highly mutated in cancer, particularly clear cell renal carcinoma. PBRM1 is a member of the SWI/SNF subcomplex, PBAF (PBRM1-Brg1/Brm-associated factors), and is characterized by six tandem bromodomains. Here we establish a role for PBRM1 in epithel...
Autores principales: | Porter, Elizabeth G., Dhiman, Alisha, Chowdhury, Basudev, Carter, Benjamin C., Lin, Hang, Stewart, Jane C., Kazemian, Majid, Wendt, Michael K., Dykhuizen, Emily C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514269/ https://www.ncbi.nlm.nih.gov/pubmed/31077944 http://dx.doi.org/10.1016/j.isci.2019.04.027 |
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