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LW6 enhances chemosensitivity to gemcitabine and inhibits autophagic flux in pancreatic cancer

The efficacy of gemcitabine therapy is often insufficient for the treatment of pancreatic cancer. The current study demonstrated that LW6, a chemical inhibitor of hypoxia-inducible factor 1α, is a promising drug for enhancing the chemosensitivity to gemcitabine. LW6 monotherapy and the combination t...

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Detalles Bibliográficos
Autores principales:	Zhang, Xianbin, Kumstel, Simone, Jiang, Ke, Meng, Songshu, Gong, Peng, Vollmar, Brigitte, Zechner, Dietmar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514270/ https://www.ncbi.nlm.nih.gov/pubmed/31193017 http://dx.doi.org/10.1016/j.jare.2019.04.006

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