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Enterococcal PcfF Is a Ribbon-Helix-Helix Protein That Recruits the Relaxase PcfG Through Binding and Bending of the oriT Sequence

The conjugative plasmid pCF10 from Enterococcus faecalis encodes a Type 4 Secretion System required for plasmid transfer. The accessory factor PcfF and relaxase PcfG initiate pCF10 transfer by forming the catalytically active relaxosome at the plasmid’s origin-of-transfer (oriT) sequence. Here, we r...

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Detalles Bibliográficos
Autores principales: Rehman, Saima, Li, Yang Grace, Schmitt, Andreas, Lassinantti, Lena, Christie, Peter J., Berntsson, Ronnie P.-A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514445/
https://www.ncbi.nlm.nih.gov/pubmed/31134011
http://dx.doi.org/10.3389/fmicb.2019.00958