Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don'ts in Clinical Practice

In radiation oncology, little is known about possible difficulties in patients with Osteogenesis Imperfecta (OI). Because radiotherapy can cause various side-effects including bone, soft tissue and cardiovascular toxicities, we foresee that patients with OI may experience even more acute and late si...

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Autores principales: Lodeweges, Joyce E., van Dijk, Fleur S., Verhoeff, Joost J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514481/
https://www.ncbi.nlm.nih.gov/pubmed/31123459
http://dx.doi.org/10.1159/000499903
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author Lodeweges, Joyce E.
van Dijk, Fleur S.
Verhoeff, Joost J.C.
author_facet Lodeweges, Joyce E.
van Dijk, Fleur S.
Verhoeff, Joost J.C.
author_sort Lodeweges, Joyce E.
collection PubMed
description In radiation oncology, little is known about possible difficulties in patients with Osteogenesis Imperfecta (OI). Because radiotherapy can cause various side-effects including bone, soft tissue and cardiovascular toxicities, we foresee that patients with OI may experience even more acute and late side-effects due to pre-existing problems. We present two cases of radiotherapy in patients with OI, measured the effects of radiation on their bone mineral density and provide clinical recommendations for patient tailored radiotherapy strategies in patients with OI.
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spelling pubmed-65144812019-05-23 Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don'ts in Clinical Practice Lodeweges, Joyce E. van Dijk, Fleur S. Verhoeff, Joost J.C. Case Rep Oncol Case Report In radiation oncology, little is known about possible difficulties in patients with Osteogenesis Imperfecta (OI). Because radiotherapy can cause various side-effects including bone, soft tissue and cardiovascular toxicities, we foresee that patients with OI may experience even more acute and late side-effects due to pre-existing problems. We present two cases of radiotherapy in patients with OI, measured the effects of radiation on their bone mineral density and provide clinical recommendations for patient tailored radiotherapy strategies in patients with OI. S. Karger AG 2019-04-17 /pmc/articles/PMC6514481/ /pubmed/31123459 http://dx.doi.org/10.1159/000499903 Text en Copyright © 2019 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Lodeweges, Joyce E.
van Dijk, Fleur S.
Verhoeff, Joost J.C.
Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don'ts in Clinical Practice
title Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don'ts in Clinical Practice
title_full Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don'ts in Clinical Practice
title_fullStr Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don'ts in Clinical Practice
title_full_unstemmed Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don'ts in Clinical Practice
title_short Radiotherapy Late Effects and Osteogenesis Imperfecta: Dos and Don'ts in Clinical Practice
title_sort radiotherapy late effects and osteogenesis imperfecta: dos and don'ts in clinical practice
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514481/
https://www.ncbi.nlm.nih.gov/pubmed/31123459
http://dx.doi.org/10.1159/000499903
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AT vandijkfleurs radiotherapylateeffectsandosteogenesisimperfectadosanddontsinclinicalpractice
AT verhoeffjoostjc radiotherapylateeffectsandosteogenesisimperfectadosanddontsinclinicalpractice

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